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Five Choice Serial Reaction Time Task (5CSRTT)
The Five Choice Serial Reaction Time Task (5CSRTT) is a visuospatial attention test that has been widely used to study the behavioral traits associated with attention deficit hyperactivity disorder (ADHD) such as attention and impulse control. It offers effective clinical instruction on Alzheimer’s disease, Depression, Huntington’s disease, Schizophrenia, ADHD and OCD.
The 5/9 hole behavioral test, also called as 5CSRTT is a widely used behavioral instrument for evaluating the cognitive functions, learning and memory abilities of rodents (such as mice or rats). This 5CSRTT records the exploration and selection behaviors of animals in different holes, and can be used for various studies.
Applications
Assessing spatial memory and cognitive abilities
Examining the potential effects of drugs on cognition
Simulating cognitive deficits in neurological diseases such as Alzheimer’s disease,
Analyzing behavioral changes caused by environmental or stress factors
Exploring the influence of genetic background on learning and memory
Revealing psychological mechanisms such as decision-making and risk assessment.
Features
Our 5CSRTT device consists of an operant conditioning chamber with five nose poke apertures, each nose poke apertures comes with a stimulus LED light as well as an infrared nose poke sensor. Food pellets or liquid can be offered as reward on the condition that the rodent correctly explores a hole within a preset time. The shocker floor grid allows for punishment in the experiment. The removable feces and urine tray below this grid allow for easy cleaning.
Multiple standard trials are included in 5CSRTT, contains Shaping, Initial Touch Training, Must Touch Stimuli, Training to baseline ,Training 1/2, easy operation as no programming parameter setting. Customized trials available.
Animal information can be edited freely, containing group, gender, age, weight etc..
Various behavior of animals in the experiment can be recorded in real time, events, synchronized time, easy to be used with other devices.
Summary of results: statistics of trials for each cage including count and percentage of each response (correct, premature, incorrect, and omission)
Experiment results are exportable as xls. file for easy data statistics.
Area detection sensor is equipped in 5CSRTT, which can be applied to hole contact and reward area etc..
Sequential activity: The detailed activities for each trial.
Shock Stimulus
Constant Current from 0.01 to 4.0 mA in 0.05mA step.
Current control can be controlled programmatically or manually.
Light Stimulus
Sound-proof insulation cubicle, >30dB.
Sound frequency 500-16000HZ, sound intensity 0-100HZ.
Air circulation: one fan on the back wall.
Reward Mode
Liquid & Pellet
The user configures what condition(s) a pellet is dispensed.
Food magazine with precision sensors to detect food drop, animal exploration and eating etc.
The software captures and reports nose poke events on pellets.
