Sleep Deprivation Device

The sleep deprivation device consists of a clear acrylic chamber atop a motor and screen to set time and rotations of a bar inside the chamber to prevent the rodent from sleeping in a safe way. Food and water apparatuses are available to allow long-term experimentation. Our device equips with a circadian rhythm light control system, and it can be used for optogenetic experiments and calcium ion imaging experiments.

Application

• Circadian Rhythm Research: Study phase shifts, sleep-wake cycles, jet lag models
• Sleep Disorders Modeling: Investigate insomnia, REM behavior disorder, narcolepsy
• Metabolic Studies: Explore connections between sleep and obesity, glucose tolerance, insulin resistance
• Neurological & Psychological Research: Assess sleep’s role in depression, anxiety, memory loss, PTSD, and cognitive decline
• Pharmacology & Drug Screening: Evaluate sedatives, stimulants, and cognitive enhancers under sleep-deprived conditions

Features

• Programmable Rotating Bar System
  Adjustable speed (1–20 cm/s), direction (CW/CCW/random), and pause intervals (0–240s)
• AI-Integrated Interface
  Real-time control and automatic recording; user-friendly 5” touchscreen
• Intelligent detect the sleep state
  Equips with the camera to detect the animal is asleep or not and automatically initiates sleep deprivation operation (Intelligence version)
• Dual Use for Sleep Deprivation & Sleep Fragmentation
  Supports various experimental protocols (total deprivation, REM-specific, intermittent)
• Ultra-Quiet Operation
  Noise level <30 dB to ensure minimal stress
• Housing Chamber
  Modular design supports 8–12 mice or 4–6 rats; food & water access included.

Advantages

• Fully Automated Protocols–Eliminate operator error and manual handling
• Low Stress to Subjects–Gentle nudging instead of forced locomotion
• Compatible with High-Level Analysis Tools–EEG/EMG, optogenetics, fiber photometry
• Supports Long-Term Studies–Food, water supplied in the unit
• Wide Application Versatility–Suitable for behavioral, metabolic, and pharmacological research