Q1: How to perform a tail suspension test in mice?
A: Mice are suspended by their tail in the chamber and the Mice innately attempt to escape from this adversive situation. Their activity is recorded, and periods of immobility are measured to assess behavioral despair. 4 Mice can be conducted at the same time to be recorded the activiey.
Q2: What is the difference between FST and TST?
A: The forced swim test uses water immersion to induce immobility, while the tail suspension test suspends the mouse by its tail to measure immobility time. Both are validated depression models but may suit different experimental needs.
Q3: Can this system be automated?
A: Yes, it is fully compatible with our Video Tracking Software for automated tracking and scoring.
Q4: Why use FST and TST in depression research?
A: Both tests are sensitive to antidepressants and have strong translational relevance to clinical outcomes, making them standard tools in preclinical behavioral pharmacology.
