The Porsolt Forced Swim Test (FST) apparatus and Tail Suspension Test (TST) apparatus are gold-standard tools for rodent depression behavioral research.
In the Porsolt forced swim test, a mouse or rat is placed in a water-filled cylinder where escape is impossible. After initial struggling, the animal exhibits a state of immobility, reflecting behavioral despair—a widely accepted model for screening antidepressant drugs.
Similarly, the tail suspension test measures immobility when a mouse is suspended by its tail, providing a rapid and sensitive method for TST behavioral test studies.
Both methods are highly sensitive to most antidepressants, with strong correlation to clinical efficacy, making them essential in preclinical neurobehavioral pharmacology.
Features & Benefits
Application
Q1: How to perform a forced swim test in mice?
A: Mice are placed individually into a transparent cylinder filled with water at a controlled temperature. Their activity is recorded, and periods of immobility are measured to assess behavioral despair. Our apparatus ensures standardized water depth, cylinder size, and high-resolution video tracking.
Q2: What is the difference between FST and TST?
A: The forced swim test uses water immersion to induce immobility, while the tail suspension test suspends the mouse by its tail to measure immobility time. Both are validated depression models but may suit different experimental needs.
Q3: Is the apparatus suitable for both rats and mice?
A: Yes, we provide two cylinder sizes for rats (200 mm) and mice (130 mm), along with adjustable tail suspension settings.
Q4: Can this system be automated?
A: Yes, it is fully compatible with our Video Tracking Software for automated tracking and scoring.
Q5: Why use FST and TST in depression research?
A: Both tests are sensitive to antidepressants and have strong translational relevance to clinical outcomes, making them standard tools in preclinical behavioral pharmacology.
Item No. | Product |
SA209M | Porsolt Forced Swim Test for Mouse |
SA209R | Porsolt Forced Swim Test for Rat |
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