Lab Animal Equipment
Lab Animal Equipment
  • Plethysmometer for Evaluation Paw Volume
  • Plethysmometer for Evaluation Paw Volume
  • Plethysmometer for Evaluation Paw Volume
  • Plethysmometer for Evaluation Paw Volume
  • Plethysmometer for Evaluation Paw Volume
  • Plethysmometer for Evaluation Paw Volume

Plethysmometer for Evaluation Paw Volume

The Plethysmometer is an useful instruments designed to measure small change in paw volume, it is typically used to measure the inflammation of the paws in rodents which is experimentally induced. This test provides effective evaluation on screening potential antipyretic, anti-inflammatory, anti-oedema properties of pharmacological substances.

Overview

The Plethysmometer, also call as Paw Edema Meter, is a precise and user-friendly instrument designed to measure small volume changes in experimental animals. It is commonly used in pharmacology and inflammation studies to evaluate paw swelling induced in rodents. This system provides accurate, repeatable, and efficient data for screening the anti-inflammatory, anti-edema, and antipyretic properties of potential therapeutic compounds.

By combining modern sensing technology with the physical principles of Newton’s laws of motion and Archimedes’ law, the Plethysmometer ensures exceptional measurement precision and reliability. The system converts buoyancy changes into measurable forces, enabling accurate calculation of paw volume in real time.

Application:

  • Pharmacological testing of anti-inflammatory and anti-edema compounds
  • Preclinical research on pain and inflammation in rodents
  • Evaluation of drug efficacy in paw edema models
  • Laboratory teaching and physiological experiments involving volume displacement measurement
  • Suitable for both rats and mice, it provides a simple, non-invasive method for obtaining quantitative results with minimal stress to the animal.

Features & Benefits:

  • Ultra-High Accuracy – Measures volume changes as precise as 1 μL, ensuring reliable and repeatable results.
  • Smart Touchscreen Interface – 7-inch high-resolution display for intuitive operation and clear data visualization.
  • Flexible Operation – Choose between automatic or pedal start to match experimental preferences.
  • Dual Animal Compatibility – Designed for both rats and mice with dedicated restrainers.
  • Instant Printing & Data Storage – Save up to 200 data sets and print results instantly for documentation.
  • Automatic Data Analysis – Calculates mean and standard deviation in real time, streamlining workflow.
  • Modern Sensing Technology – Delivers higher precision and easier operation compared with other suppliers.
Specification

Technical Specifications

Display 7 inch touch screen display, resolution 800*480.
Volume 0-70ml
Measurement accuracy 1µl
Measuring cup inner diameter 40mm
Integrated battery Deviation < 0.083 seconds/hour
Starting Automatic or pedal switch
Mini printer Instant print & memory print
Memory 200 data
Data statistics Automatically calculates the average value and standard deviation in real time
Data store USB interface, data can be stored in the PC
Control Unit Dimensions 350×300×145mm
Power Supply 110V/ 220V, 50/60Hz
FAQ
Q1: What is a plethysmometer used for?
A plethysmometer measures small volume changes, typically used to assess paw edema or inflammation in rodents during pharmacological studies.
 
Q2: Can this plethysmometer be used for both rats and mice?
Yes, the BioMed Plethysmometer includes dedicated restrainers for both rats and mice.
 
Q3: What is the measurement accuracy of this system?
The system provides ultra-High accuracy up to 1 μL, ensuring precise detection of even minimal swelling changes.
 
Q4: Does it include software for data analysis?
The plethysmometer includes built-in data statistics and automatic calculation functions, easily to review the paw edema volume changes.
 
Q5: How does it differ from other plethysmometer systems?
The measurement principle is different. Our Plethysmometer measure the volume of the paw through the force and reaction force using ultra high precision pressure sensor, do not need other relevant standard devices, only need to use pure water in the cup.
Reference

Design and Synthesis of Novel Double-Ring Conjugated Enones as Potent Anti-rheumatoid Arthritis Agents

https://pubs.acs.org/doi/full/10.1021/acsomega.2c05492

How to Order

Ordering Information

Item No. Product
SA701 Plethysmometer for both Rat and Mouse

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