Lab Animal Equipment
Lab Animal Equipment
  • drug dependence rat
  • Conditioned Place Preference
  • Conditioned Place Preference rat
  • Conditioned Place Preference
  • drug dependence rat
  • Conditioned Place Preference
  • Conditioned Place Preference rat
  • Conditioned Place Preference

Conditioned Place Preference (CPP)

Conditioned Place Preference (CPP) System is a high-precision behavioral neuroscience apparatus designed for drug addiction studies, reward learning, and drug-seeking behavior research. CPP is one of the most widely used paradigms in psychopharmacology, enabling researchers to quantify drug-induced reinforcement, contextual learning, and motivational states in rodents.

Overview

In the Conditioned Place Preference protocol, animals (rats or mice) receive psychotropic or rewarding drug administration (e.g., morphine) within a specific chamber. Through repeated conditioning, rodents develop a measurable place preference driven by the drug’s reward value. Our CPP box provides a controlled, automated, and reproducible environment where researchers can precisely track chamber preference, locomotor activity, and reward-associated learning.
The integrated IR thermal imaging tracking module delivers accurate multi-chamber tracking, while the smart automatic door system minimizes human interference—ensuring high-quality behavioral data for advanced neuroscience and addiction research.

Application

  • Drug addiction research / substance dependence
  • Reward learning and reinforcement mechanisms
  • Drug-seeking behavior and contextual conditioning
  • Motivational behavior assays
  • Psychotropic drug screening
  • Positive/negative reinforcement
  • Calcium imaging / optogenetics synchronized behavioral tests
  • Rodent learning and memory experiments
  • Behavioral phenotyping for CNS disorders

Features & Advantages

  • High-Precision Behavioral Tracking
    IR thermal imaging ensures accurate movement detection
    Reliable tracking even in low-light or high-contrast environments
    Multi-chamber parallel tracking for high-throughput CPP studies
  • Minimized Human Interference
    Anti-clip automatic doors reduce disturbance
    Ensures more stable reward-associated behavior measurement
  • Flexible Experimental Setup
    Modular chamber design
    Multiple texture floors support contextual discrimination learning
    Suitable for CPP, CPA (Conditioned Place Aversion), and hybrid protocols
  • Advanced Software Analysis
    Independent signal detection for each chamber
    Export formats: CSV, PDF, JPG trajectory maps
    Full synchronization with optogenetic or Ca²⁺ imaging devices
    One-click generation of:
    1)Chamber preference plots
    2)Distance/velocity metrics
    3)Reward learning curves
  • Comprehensive Behavioral Data Output
Specification

General System

  • Rodent compatibility: Rats & Mice
  • Maximum capacity: Up to 16 CPP chambers
  • Chamber materials designed for high-contrast contextual cues

Tracking Module

  • IR thermal imaging sensor with core recognition algorithm
  • Accurate multi-zone / multi-chamber tracking
  • Automatic data mapping for left/right chambers
  • Real-time tracking indicator

Automatic Door System

  • Anti-clip protection
  • Opening/closing speed: 2–8 cm/s
  • Closing distance: 1–10 cm
  • Noise: <65 dB

Chamber Flooring Options

  • Square grid
  • Round grid
  • Bar grid

Controller & Connectivity

  • Independent channel software control
  • TTL trigger output for:
    1)Calcium Imaging
    2)Optogenetics
    3)Fiber Photometry
    4)Neural Recording Systems
  • Independent signal detection control in each box to precise detect the signal in the experiment.
  • Independent software operated for separated channel.
  • Shuttle passive, learning helplessness are integrated in this software for different experiment.
  • Data can be exported to .csv format for further analysis or .pdf format.
  • Trajectory charts and bar charts are saved in .jpg format.
  • Can be connected with Calcium Imaging, Optogenetic etc..

Test Parameters

•Total distance(mm)                                              •Average speed (mm/s)

•Running time in left chamber(s)                          •Running time in right chamber(s)

•Time percentage in left chamber (%)                  •Time percentage in right chamber (%)

•Distance in left chamber(mm)                             •Distance in right chamber(mm)

•Distance percentage in left chamber (%)            •Distance percentage in right chamber(%)

•Number of times for total shuttle/left chamber /right chamber

Size

  Automated CPP for Mouse Automated CPP for Rat
Left chamber 20*20*25cm 30*30*37cm
Middle chamber 8*20*25cm 8*30*37cm
Right chamber 20*20*25cm 30*30*37cm
FAQ

1. What animals are compatible with the Conditioned Place Preference System?
Both rats and mice are fully supported.

2. Can the system be used for both CPP and CPA?
For Conditioned Place Aversion experiments, please contact us for more details and we can customize it.

3. Does the system integrate with optogenetics or calcium imaging?
Yes. A TTL trigger allows synchronization with optogenetic stimulation, Ca²⁺ imaging, or other neural recording systems.

4. How many chambers can be operated simultaneously?
Up to 16 independent chambers for high-throughput experiments.

5. What data formats are supported?
Data can be exported as CSV, PDF, and trajectory files as JPG.

6. Is the system suitable for drug-seeking behavior research?
Absolutely. It is specifically designed for:
Drug addiction
Dependence
Reward reinforcement
Motivational learning

Reference

The Conditioned Place Preference (CPP) test is a widely accepted model for assessing drug-induced reward and psychotropic dependence in rodents. It is frequently cited in studies on addiction, reinforcement mechanisms, and drug-seeking behaviors, making it a valuable tool in both pharmacological research and behavioral neuroscience.

How to Order
Item No. Product
SA213S Automated Conditioned Place Preference (1 cage, including  CPP cage with automated door, IR thermal imaging sensor, and software.) Sound Isolation cubicle is optional.

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