In animal models, changes in voluntary wheel-running activity are often used as indicators of disease. Our wireless running wheels offer the most cost-effective solution for monitoring the voluntary activity of rodents.
This intelligent low-profile wireless running wheel is to study the circadian rhythm of experimental animals, which is applicable for the activity monitoring on Mice. Being adapt to most individually ventilated cages (IVCs), it provides quantitative measurement of mouse running levels, with 1 minute to 24 hours activity quantification.
Our Top-wheel running wheel serves as effective and economical tools in analyzing the animal’s circadian rhythm and the effects on physiology and behavior.
Top-wheel wireless running wheel system provides 7× 24-hour uninterrupted monitoring, with accurate data recording and adjustable statistical period. Equipped with wireless USB Bluetooth hub, each hub supports 32 running wheels, and each PC supports 4 hubs. Based on the wireless transmitter, the running wheel system seamlessly sends activity data from the cages to the PC, not wires or cables needed.
Application
• Neuroscience research
Assessment of motor dysfunction in Parkinson’s disease model mice, quantifying drug efficacy through long-term monitoring of changes in running wheel usage frequency.
Data dimensions: Daily running distance decrease > 50% indicates significant motor impairment.
• Metabolism and obesity research
Combined with the metabolic cage system, simultaneously analyze the correlation between exercise volume and energy expenditure, as well as feeding behavior.
• Psychopharmacology experiments
Antidepressant drug screening: Increased running activity in depression model mice reflects the drug’s improvement of motivational deficiency (Anhedonia).
• Circadian rhythm analysis
Continuous monitoring for more than 72 hours, analyze voluntary activity and circadian rhythm.
Applicable on circadian rhythm measurement in mouse standard ventilated cage.
Efficient Bluetooth management: A single Bluetooth hub can manage up to 32 running wheels, and 4 hubs per computer.
Accurate data recording: Supports quantification of running levels to determine how they correlate with behavioral changes, and users can customize the statistical period, ranging from 1 minute to 24 hours.
Detachable battery: Support up to 7×24 hours of uninterrupted monitoring for long-term experiments.
Wireless design: Device can be flexibly placed in different positions of IVCs, improve the flexibility of the experiment.
Data record: wheel counts (forward and reverse), total running time, fastest speed, remaining battery etc.
Offline data analysis is available.
Excel format exportable, make it more convenient to analyze the animal’s circadian rhythm and the effects on physiology and behavior.
Easy to clean: Separated design of running wheel and support base which can be washed easily. Wipe wheel transmitter with sanitation cloths.
Energy efficient: powered by three AAA batteries included.
Size:
Running wheel diameter: 15.24cm (6 inches)
Support base: 9cm x 9cm x 7cm
Overall size: 15cm x 15cm x 10cm
