As advised by A. MOQRICH, and published in Moqrich et al (Science 2005, 307: 1468-72), the thermal place preference test (TPPT) was designed to finely assess thermal sensitivity in rodents. It can detect, quantify, and differentiate behavioral responses to cold stimuli between sham and chronic constriction injury (CCI) rodents.
The Thermal Place Preference Test, based on two Hot Cold Plate (Temperature range from -5°C to 65 °C),allows researchers to work on free moving animals (Rats and Mice) to choose their preferred place between 2 compartments set a different temperature. Our TPPT adopts dynamic infrared scanning tracking technology to record the location of the rodents and automatically analyze the staying time and times in each compartment. TPPT enables a fine-grained assessment of thermal sensitivity that is relevant to the pathophysiological exploration of animal pain models and to the pharmacological assessment of analgesic drugs.
Application: Chronic constriction injury, Cold allodynia, Neuropathic pain, Analgesic drug screening.
Thermal Place Preference Test, also call as 2 Temperatures Choice Nociception Test, can be considered as an evolution of the Hot Cold plate test, it is a test to study pain thresholds in rodents (mouse and rat) by assessing temperature preference.
Features and Benefits
Features | Benefits |
Capacitive 8-inch LCD display, resolution: 800×600 | Big display for easy operation |
Wide range of temperatures (-5° to -65°) | Able to conduct any sort of thermal sensitivity experiment, including severe cold allodynia. |
Adopts precise PID control algorithm, will continuously collect temperature feedback to control heating/cooling. | Control the current temperature more accurately. |
Adopts high-performance 32-bit microcomputer control chip for temperature control. | Ensure the accurate temperature. |
Adopts dynamic infrared scanning tracking technology. | Location of the rodents, staying time and times in each compartment automatically recorded. |
Experimental temperature of placement on the plate and the first sign of nocifensive response such as paw licking or jumping can be recorded in real time. | |
Data extraction from the Thermal Place Preference is straightforward by using a USB drive, in CSV format. | Possibility to open files in Excel. |
Application | Rat or Mouse |
Commands | 8-inch LCD display, resolution 800*600 |
Power | 100-240 VAC, 50-60Hz, 300W |
Sound Level | < 60 dB (A) |
Plate Temp. Range | -5.0°C to +65°C (in 0.1°C steps) |
Speed | Fixed, progressive |
Start/Stop | By foot pedal switch |
Detection | High-performance 32-bit microcomputer control chip |
Time display | 0.01~600.00s |
Time Display standard deviation | <0.02 ‰ Seconds |
Experimental data | Time, temperature, mean, maximum value, minimum value |
Place Preference data | Dwell time/ Cross Times/Times of Left/Right compartment |
Position display | Current staying location/Time display |
Data export | By USB flash drive |
Data storage | 100 data |
Container size | 530×230×260mm (L x W x H) | |
Middle door thickness | 15mm | |
Weight | 23kg |
Item No. | Product Description |
SA707 | Thermal Place Preference for Mice and Rats |
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